Signal Radar · SIG-2026-006

PROSPR THRIVE is developing a healthspan score from harmonized longitudinal data

92/100 priorityHealthspan MeasurementActive R&D2026-02-24

Stanford-led THRIVE will harmonize existing datasets to generate a PROSPR-IC healthspan score and test its accuracy and intervenability in a one-year lifestyle intervention supported by in-home digital assessment.

Why it matters

A validated, intervention-responsive healthspan score could materially change trial design, product claims, reimbursement evidence, and how healthspan is measured outside decades-long studies.

Decision implication

Track the construction, validation, endpoint properties, and public availability of the PROSPR-IC score.

Who or what is affected

  • ARPA-H
  • Stanford
  • researchers
  • digital-health developers
  • regulators

Evidence and sources

E5 — official federal award description

P4L distinguishes the sourced event from the interpretation above. Participation, funding, proposed policy, or program inclusion does not by itself establish clinical effectiveness.

What P4L is watching next

  • Score definition
  • validation results
  • intervention responsiveness
  • regulatory acceptance.

Related proof records

Last verified: 2026-08-08 · Version 1.0 · Stable ID: SIG-2026-006