{
  "signal_id": "SIG-2026-017",
  "observed_date": "2026-01-13",
  "category": "Agentic AI + Clinical Care",
  "title": "ARPA-H ADVOCATE targets FDA-authorized clinical agentic AI for cardiovascular care",
  "what_changed": "ARPA-H's ADVOCATE program is designed to develop clinical AI agents that can autonomously support and adjust aspects of cardiovascular care, alongside a supervisory AI overseer.",
  "why_it_matters": "This moves agentic AI from administrative copilots toward clinically consequential autonomous actions with explicit safety, efficacy, monitoring, and regulatory requirements.",
  "affected_actors": [
    "ARPA-H",
    "FDA",
    "cardiovascular health systems",
    "AI developers",
    "clinicians",
    "patients"
  ],
  "decision_implication": "Create a dedicated agentic-AI adoption standard covering authority boundaries, human escalation, post-deployment monitoring, evidence, liability, workflow, and regulatory status.",
  "status": "Active program",
  "evidence_class": "E5 — official ARPA-H source",
  "impact": 5,
  "immediacy": 4,
  "relevance": 5,
  "novelty": 5,
  "adoption_leverage": 5,
  "priority_score": 96,
  "sources": [
    "https://arpa-h.gov/explore-funding/programs/advocate"
  ],
  "public_slug": "/signal/2026-01-13-advocate-agentic-ai/",
  "watch_conditions": [
    "Awardees",
    "supervisory-agent architecture",
    "FDA pathway",
    "clinical validation",
    "deployment sites."
  ],
  "last_verified": "2026-08-08",
  "version": "1.0"
}