{
  "signal_id": "SIG-2026-005",
  "observed_date": "2026-02-24",
  "category": "Healthspan Research + Clinical Translation",
  "title": "ARPA-H awards seven PROSPR teams and up to $144M to accelerate healthspan trials",
  "what_changed": "ARPA-H funded seven PROSPR teams to identify early aging markers, build healthspan measures, and test interventions using accelerated and decentralized trial designs.",
  "why_it_matters": "The federal government is explicitly funding infrastructure intended to make healthspan a clinically testable and potentially regulatable therapeutic target.",
  "affected_actors": [
    "ARPA-H",
    "PROSPR teams",
    "FDA/regulators",
    "research institutions",
    "healthspan industry"
  ],
  "decision_implication": "Track biomarkers, endpoint qualification, trial methods, regulatory precedents, and commercialization pathways created by PROSPR.",
  "status": "Active R&D",
  "evidence_class": "E5 — official federal source",
  "impact": 5,
  "immediacy": 3,
  "relevance": 5,
  "novelty": 5,
  "adoption_leverage": 5,
  "priority_score": 92,
  "sources": [
    "https://arpa-h.gov/news-and-events/research-teams-add-more-healthy-years-americans-lives-they-age"
  ],
  "public_slug": "/signal/2026-02-24-arpa-h-prospr-awards/",
  "watch_conditions": [
    "Milestones",
    "biomarker validation",
    "trial recruitment",
    "regulatory interactions",
    "published results."
  ],
  "last_verified": "2026-08-08",
  "version": "1.0"
}